Certain acne products that contain benzoyl peroxide or salicylic acid can rarely cause serious and sometimes life-threatening allergic reactions or severe irritation. Before first use, you may need to follow certain steps to make sure you do not have an allergic reaction. Use Duac gel as you were told by your doctor or read the package label. Discuss any questions or concerns with your doctor. Mild burning, dryness, peeling, or redness of the skin. Transient exacerbation of acne may occur, generally during initial therapy period. Check with your doctor or pharmacist if you think any of these may apply to you.
It is not for use by children under 12 years. Don't breast-feed while you are using Isotrex. Advise patient to take sips of water frequently, suck on ice chips or sugarless hard candy, or chew sugarless gum if dry mouth occurs.
Stiefel Laboratories Ireland Ltd. Duac gel may bleach hair or colored fabric. Avoid getting Duac gel in your hair or on your clothes. Instruct patient to discontinue any other acne medications including OTC topical preparations before starting therapy. Glaxo Operations UK Ltd.
The name of your medicine is Isotrex Gel. Use Isotrex once or twice each day. Do not leave in direct sunlight. Tell your doctor or dentist that you take Duac gel before you receive any medical or dental care, emergency care, or surgery. Isotretinoin may further irritate these conditions.
Card Scheme at: www. Repackaged by Servipharm Ltd. Isotrex if you are pregnant. The major metabolite is 4-oxo-isotretinoin. CYP2C8, CYP2C9, CYP3A4, and CYP2B6 involved in isotretinoin metabolism. Isotrexin on any irritated areas of skin. This includes any possible side effects not listed in this leaflet. It is especially suitable if you have dry skin. Store Duac gel at 77 degrees F 25 degrees C. Do not freeze. Store away from heat, moisture, and light. Do not store in the bathroom. Keep tightly closed. Throw away any unused portion after 2 months. Keep Duac gel out of the reach of children and away from pets.
Inform patient that contact lens tolerance may decrease. This includes medicines bought without a prescription. Isotrexin in your mouth, rinse at once with plenty of water. Abdominal pain, ataxia, cheilosis, dizziness, facial flushing, headache, vomiting. Not all pack sizes may be marketed. Isotrexin on sensitive areas of skin such as the neck. Do not use Isotrexin after the expiry date printed on the tube and the carton. Cream called Isotrex in this leaflet. Fucidin Cream is supplied in tubes of 15g. Talk with your doctor before you use any other topical acne medicines or cleansers on your skin. Isotrex on sensitive areas of skin such as the neck. Do not get Duac gel in your mouth, eyes, nose, or on your lips.
Do NOT use more than the recommended dose or apply more often than prescribed without checking with your doctor. Using Duac gel too often may make your acne worse. Isotrexin contains butylated hydroxytoluene E321. Give medication with meals. Bleeding and inflammation of the gums, colitis, esophageal ulceration, esophagitis, hepatitis, ileitis, inflammatory bowel disease, nausea, nonspecific GI symptoms, pancreatitis. If used at the same time, it may make skin irritation worse. Cashel Road, Dublin 12, Ireland. Isotrex on any irritated areas of skin. Isotrexin is a trademark of Stiefel Laboratories, Inc. Isotrex on any irritated areas of skin. For example if you have cuts or grazes, or sunburn.
Isotretinoin must be prescribed and dispensed by prescribers and pharmacies registered with and activated by the FDA-restricted distribution program, iPLEDGE. Patients must be registered and meet all requirements of iPLEDGE. Consult the package insert for details. Only use Isotrexin on your skin. Duac gel is for external use only. Avoid contact with the eyes, nose, mouth, and other mucous membranes. If you get Duac gel in any of these areas, rinse them right away with cool water. If this happens, stop using the medicine for a few days. Because of isotretinoin's teratogenicity, and to minimize fetal exposure, isotretinoin is approved for marketing only under a restricted distribution program, called iPLEDGE, approved by the FDA. Isotretinoin must be prescribed by prescribers and dispensed by pharmacies registered and activated with the iPLEDGE program, and must only be dispensed to patients who are registered and meet all the requirements of iPLEDGE. KEEP OUT OF THE SIGHT AND REACH OF CHILDREN. The name of your medicine is Isotretinoin Gel. This product is flammable. This leaflet was last revised in October 2014. This includes medicines obtained without a prescription. Have been associated with pseudotumor cerebri or papilledema in isotretinoin patients. If you have any questions about Duac gel, please talk with your doctor, pharmacist, or other health care provider. These effects are normal. Advise patient to be seen by health care provider monthly and have a urine or serum pregnancy test performed each month to confirm negative pregnancy status. If you get any side effects, talk to your doctor or pharmacist.
Isotretinoin Gel throughout the following leaflet. Medicines should not be disposed of via wastewater or household waste. You should keep using the medicine until your doctor tells you otherwise. Then next use this medicine at the usual time. Advise patient to take medication with meals. Keep out of the sight and reach of children. Isotrex may further irritate these conditions. Avoid skin products that contain alcohol, spices or lime. Talk to a doctor if you swallow a lot of Isotretinoin. Ask your health care provider any questions you may have about how to use Duac gel.
If you do get sunburnt, stop using Isotrex until your skin is better. If your symptoms do not improve or if they become worse, check with your doctor. Wash the area with a mild soap and warm water, and dry gently. These effects can occur on the area of skin where you use the gel. Fucidin Cream contains fusidic acid. It is a type of antibiotic. Isotrex contains cetostearyl alcohol. Talk to a doctor if you swallow a lot of Isotrexin. PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Duac gel while you are pregnant. It is not known if this medicine is found in breast milk after topical use. Do not breast-feed while using Duac gel. May increase toxic effects; do not take with isotretinoin. For example if you have cuts or grazes, or sunburn. Ask your pharmacist how to dispose of medicines no longer required. Clinical hepatitis possibly related to isotretinoin therapy has been reported. Mild to moderate elevations of liver enzymes have been seen. HDL and approximately 7% showed an increase in cholesterol levels. Perform blood lipid determinations before isotretinoin is given, and then at regular intervals. Only use Isotrex on your skin.
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Talk to your doctor or pharmacist before using Isotrexin. Your eye may sting. Prior to use, have patient complete a consent form included with package insert. Ask your doctor or pharmacist for advice before taking any medicine, while you are pregnant or breastfeeding.
Decreased HDL, RBC parameters, and WBC counts; elevated CPK, fasting blood sugar, platelet counts, sedimentation rates, serum cholesterol, and triglycerides; increased alkaline phosphatase, ALT, AST, gamma-glutamyl transpeptidase, or LDH; hyperuricemia; thrombocytopenia. You should check with your doctor or pharmacist if you are not sure. Lane, Wembley, HA0 1DX.
Obtain 2 negative urine or serum pregnancy tests prior to receiving initial isotretinoin prescription and negative result for urine or serum pregnancy test each month; obtain pretreatment and follow-up lipids during fasting conditions; monitor liver function weekly or biweekly until isotretinoin response has been established; periodically determine blood glucose. Isotrexin will not work as well as it should. Continue to use Duac gel even if your condition improves. Do not miss any doses. Isotrex Gel, tell your doctor.
Reduces sebum secretion and sebaceous gland size, and inhibits sebaceous gland differentiation. Put a thin ﬁlm of gel on the affected skin, using your ﬁngertips. Caution patient against use of vitamin A, even in multivitamins, to avoid additive toxicity. Isotretinoin use has been associated with a number of cases of pseudotumor cerebri, some of which involved concomitant use of tetracyclines. Early signs and symptoms include headache, nausea, papilledema, visual disturbances, and vomiting.